Boston\u2019daki Mass General Brigham Enstit\u00fcs\u00fc ara\u015ft\u0131rmac\u0131lar\u0131, kanser te\u015fhisi i\u00e7in devrim niteli\u011finde bir \u00e7al\u0131\u015fmaya imza att\u0131. HPV-DeepSeek ad\u0131 verilen yeni bir kan testiyle, HPV kaynakl\u0131 ba\u015f ve boyun kanserlerini semptomlar ortaya \u00e7\u0131kmadan 10 y\u0131l \u00f6ncesine kadar tespit etmeyi ba\u015fard\u0131. Uzmanlar, bu erken te\u015fhis sayesinde hastalar\u0131n daha hafif tedavilerle iyile\u015fme \u015fans\u0131n\u0131n \u00f6nemli \u00f6l\u00e7\u00fcde artabilece\u011fini belirtiyor.<\/p>\n\n\n\n
Ara\u015ft\u0131rman\u0131n ba\u015fyazar\u0131 Dr. Daniel L. Faden, \u00e7al\u0131\u015fman\u0131n \u00e7\u0131\u011f\u0131r a\u00e7\u0131c\u0131 oldu\u011funu vurgulayarak, \u201cAra\u015ft\u0131rmam\u0131z, hi\u00e7bir belirti g\u00f6stermeyen ki\u015filerde HPV\u2019ye ba\u011fl\u0131 kanserleri, te\u015fhisten y\u0131llar \u00f6nce tespit edebildi\u011fimizi ilk kez kan\u0131tlad\u0131\u201d <\/em><\/strong>dedi.<\/p>\n\n\n\n \u0130nsan papilloma vir\u00fcs\u00fc (HPV), ABD\u2019deki ba\u015f ve boyun kanseri vakalar\u0131n\u0131n yakla\u015f\u0131k %70\u2019inden sorumlu. Bu oran, HPV\u2019yi en yayg\u0131n vir\u00fcs kaynakl\u0131 kanser etkeni haline getiriyor.<\/p>\n\n\n\n HPV\u2019nin neden oldu\u011fu rahim a\u011fz\u0131 kanseri, rutin tarama testleriyle erken d\u00f6nemde saptanabiliyor. Ancak ayn\u0131 vir\u00fcs\u00fcn tetikledi\u011fi ba\u015f ve boyun kanserleri i\u00e7in bug\u00fcne kadar semptomlar \u00f6ncesi tan\u0131 koyabilen bir test mevcut de\u011fildi. \u00c7o\u011fu hasta, t\u00fcm\u00f6r b\u00fcy\u00fcy\u00fcp belirti verdi\u011finde te\u015fhis alabiliyor. HPV-DeepSeek\u2019in bu a\u00e7\u0131\u011f\u0131 kapatmas\u0131, erken m\u00fcdahale ve tedavi ba\u015far\u0131s\u0131 a\u00e7\u0131s\u0131ndan \u00f6nemli bir d\u00f6n\u00fcm noktas\u0131 olarak de\u011ferlendiriliyor.<\/p>\n\n\n\n HPV-DeepSeek, t\u00fcm genom dizileme (Whole-Genome Sequencing) teknolojisini kullanarak kandaki HPV-DNA par\u00e7ac\u0131klar\u0131n\u0131 tespit ediyor. Ara\u015ft\u0131rmada biyobankadan al\u0131nan 56 kan \u00f6rne\u011fi incelendi. Bunlar\u0131n 28\u2019i ilerleyen y\u0131llarda kansere yakalanan bireylerden, 28\u2019i ise sa\u011fl\u0131kl\u0131 kontrol grubundan al\u0131nd\u0131. Sonu\u00e7lara g\u00f6re test, hastal\u0131\u011fa yakalanan grubun 22\u2019sinde HPV-t\u00fcm\u00f6r DNA\u2019s\u0131n\u0131 do\u011fru bi\u00e7imde tespit etti; kontrol grubunda ise hi\u00e7bir pozitif sonu\u00e7 bulunmad\u0131. En erken pozitif bulgu, te\u015fhisten 7,8 y\u0131l \u00f6ncesine aitti.<\/p>\n\n\n\n Yapay zek\u00e2 deste\u011fiyle geli\u015ftirilen sistemin performans\u0131 art\u0131r\u0131larak, 28 vakadan 27\u2019sinde do\u011fru sonu\u00e7 elde edildi. Baz\u0131 \u00f6rneklerde bu ba\u015far\u0131, te\u015fhisten 10 y\u0131l \u00f6ncesine kadar ula\u015ft\u0131. Uzmanlar, bu bulgunun testin y\u00fcksek do\u011fruluk ve g\u00fcvenilirlik d\u00fczeyini ortaya koydu\u011funu belirtiyor.<\/p>\n\n\n\n Ara\u015ft\u0131rmac\u0131lar \u015fu anda, ABD Ulusal Sa\u011fl\u0131k Enstit\u00fcs\u00fc (NIH) i\u015f birli\u011fiyle testin etkinli\u011fini y\u00fczlerce yeni \u00f6rnek \u00fczerinde s\u0131namaya haz\u0131rlan\u0131yor. Bu ikinci a\u015fama, HPV-DeepSeek\u2019in farkl\u0131 hasta gruplar\u0131nda do\u011fruluk oran\u0131n\u0131 \u00f6l\u00e7meyi ve klinik kullan\u0131m i\u00e7in onay s\u00fcrecini h\u0131zland\u0131rmay\u0131 ama\u00e7l\u0131yor.<\/p>\n\n\n\n Uzmanlara g\u00f6re HPV-DeepSeek, kanserin erken te\u015fhisinde devrim yaratabilecek bir potansiyele sahip. Zira bu y\u00f6ntem, hastal\u0131k ortaya \u00e7\u0131kmadan \u00f6nce v\u00fccuttaki biyolojik sinyalleri yakalayarak erken m\u00fcdahalenin kap\u0131s\u0131n\u0131 aral\u0131yor.<\/p>\n","protected":false},"excerpt":{"rendered":" Boston\u2019daki Mass General Brigham Enstit\u00fcs\u00fc ara\u015ft\u0131rmac\u0131lar\u0131, kanser te\u015fhisi i\u00e7in devrim niteli\u011finde bir \u00e7al\u0131\u015fmaya imza att\u0131. HPV-DeepSeek ad\u0131 verilen yeni bir kan testiyle, HPV kaynakl\u0131 ba\u015f ve boyun kanserlerini semptomlar ortaya \u00e7\u0131kmadan 10 y\u0131l \u00f6ncesine kadar tespit etmeyi ba\u015fard\u0131. Uzmanlar, bu erken te\u015fhis sayesinde hastalar\u0131n daha hafif tedavilerle iyile\u015fme \u015fans\u0131n\u0131n \u00f6nemli \u00f6l\u00e7\u00fcde artabilece\u011fini belirtiyor. Kanser te\u015fhisi … Read more<\/a><\/p>\n","protected":false},"author":43,"featured_media":53485,"parent":0,"menu_order":0,"template":"","format":"standard","meta":[],"categories":[1102],"tags":[],"class_list":["post-53481","almanya-haberleri","type-almanya-haberleri","status-publish","format-standard","has-post-thumbnail","category-dunya"],"_links":{"self":[{"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/almanya-haberleri\/53481","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/almanya-haberleri"}],"about":[{"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/types\/almanya-haberleri"}],"author":[{"embeddable":true,"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/users\/43"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/media\/53485"}],"wp:attachment":[{"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/media?parent=53481"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/categories?post=53481"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vasistdas.de\/en\/wp-json\/wp\/v2\/tags?post=53481"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Testin \u00e7al\u0131\u015fma prensibi<\/strong><\/h3>\n\n\n\n
Yeni faz: geni\u015f \u00f6l\u00e7ekli do\u011frulama<\/strong><\/h3>\n\n\n\n